Understanding Cancer as a Metabolic disease

In 1931, a doctor discovered the real root of cancer, and the world ignored him. His name was Dr. Otto Warburg. He won the Nobel Prize for something that should have changed cancer treatment forever. Cancer doesn’t begin with bad genes. It begins when cells can no longer use oxygen to make energy. Warburg discovered that cancer cells ferment sugar even when oxygen is available. This is called The Warburg Effect, and here is the kicker: We’re still treating cancer today as only genetic, but Warburg was right: Cancer is a metabolic disease. The big obstacle to getting established medicine to rethink cancer is that there is no money in metabolic therapy. There’s no pill or shot for Big Pharma to sell.

 The origin of the disease arises from the damage to the respiration of the cells, resulting in all the cells having to ferment, generate energy without oxygen. There energy comes from two fuels, glucose  and glutamine and can’t use fatty acids or ketone bodies. Important to move patients into ketosis, ketones cannot be used by the cancer cells. Then come in with drugs that target glucose and glutamine. These ketosis diets, water fasting, lower the blood sugar needed to drive the tumor, also powerfully anti-inflammatory. When the patient is in ketosis, use small amounts of glutamine targeting drugs. 

The mitochondria regulates energy metabolism within the cell, when the mitochondrial become dysfunctional, they revert to fermentation, fuels that don’t require oxygen those fuels are glucose and glutamine. Fermentation is the ability to get energy without oxygen. They can ferment the sugar glucose and the amino acid glutamine. If you want to kill cancer cells you must deprive them of their fermentable fuels. Origin of cancer comes from damage to the mitochondria, and so they revert back to fermentation. So you have to deprive them of their fuels glucose  and glutamine

As you slowly degrade the tumor by restricting the glucose, your other cells are getting healthier using fatty acids. Normal cells are extremely flexible in the fuels they can use. The cancer cells are massively inflexible because their oxidative phosphorylation system is corrupted. They have to root lie on fermentation in the two predominant fuels are sugar and glutamine. You can keep the body healthy while degrading the tumor.

Once you understand what the origin of the disease is, or the disorder you’re able to manage the disease without toxicity. remove the two fuels that drive fermentation metabolism while changing the body over to fatty acids and ketones.

Cancer is a mitochondrial metabolic disease where fermentation gradually replaces respiration for cellular energy.

  1. Glucose and glutamine are the major fermentable fuels for driving cancer growth

  2. Ketone bodies can replace glucose in normal cells, but not in tumor cells 

  3. ROS production is greater in tumor cells than in normal cells 

  4. Cancer mutations arises in effect, not as a cause, of destabilization cancer mutations arises in effect, not as a cause, of destabilized energy metabolism 

  5. Cancer mutations make tumor cells more vulnerable to energy stress the normal cells 

  6. The glutamine addicted neoplastic macro phage is the origin of the metastatic cancer cell